Based on these studies, the researchers concluded that CBD was effective in general pain management and caused no negative side effects. Chronic pain is defined as any pain that lasts longer than several months. Studies have found that CBD, often together with THC, is an effective pain reliever for a variety of chronic diseases. Until there is high-quality scientific evidence in humans, it is difficult to make a recommendation for the regular use of CBD in the treatment of chronic pain.
The Epidiolex patient information leaflet warns that there is a risk of liver damage, lethargy and possibly depression and suicidal thoughts, but these possible side effects also apply to other treatments for epilepsy. This research looked at the effects of cannabis-derived drugs, including CBD, for chronic neuropathic pain. In clinical trials, Sativex, an aerosol with equal parts of CBD and THC, proved to be significantly successful as an analgesic for pain related to Russo EB cancer. The aerosol, also used for pain related to multiple sclerosis, is approved in Canada to treat cancer pain and is currently undergoing trials for approval and use in the U.S.
UU Until now, pharmaceutical CBD is only approved by the FDA as an adjunctive therapy for the treatment of a special and rare form of epilepsy. Studies support a median dose of eight sprays per day for MS patients, which provides about 20 milligrams of CBD and 21.6 milligrams of THC Sativex oromucosal aerosol - Summary of Product Characteristics (Data Sheet). Both CBD and THC act on the body's natural endocannabinoid system, which plays a role in many processes, such as appetite, pain and memory. While CBD is a promising option for pain relief, research has yet to prove that it is safe and effective, and the Food and Drug Administration (FDA) has not approved CBD for pain management.
However, when researchers evaluated the average weekly worst pain scores and physical function scores from the Western Ontario and McMaster Universities Arthritis Index (WOMAC), participants who applied 250 milligrams of CBD per day experienced significant improvement over participants CBD is best taken in pill or capsule form for slow and prolonged release or as an oral tincture (infused oil containing CBD) for a more rapid onset of effect. Experts do not recommend the use of CBD oil in children, as there is little research on the effects of CBD oil on a child's developing brain. Ongoing research suggests that CBD oil for pain can help medical conditions, such as arthritis and fibromyalgia, in varying doses. They also provided guidance to the Arthritis Foundation, which recently surveyed 2,600 people with arthritis and found that 29% currently use CBD to treat arthritis symptoms.
